About GRAPE
**Medication Active Ingredient: GRAPE** **Pharmacological Class**: - Allergens [CS] - Cell-mediated Immunity [PE] - Dietary Proteins [CS] - Fruit Proteins [EXT] - Increased Histamine Release [PE] - Non-Standardized Food Allergenic Extract [EPC] **Routes of Administration**: - Sublingual - Percutaneous **Forms**: - Injection, Solution - Solution **Strengths**: - 30; 30; 30; 30; 30; 30; 30; 30; 30 [hp_X]/mL; [hp_X]/mL; [hp_X]/mL; [hp_X]/mL; [hp_X]/mL; [hp_X]/mL; [hp_X]/mL; [hp_X]/mL; [hp_X]/mL - 0.1 g/mL **Description**: The active ingredient 'GRAPE' in medications is primarily used to address allergic reactions and immune responses. It belongs to multiple pharmacological classifications including allergens, which trigger allergic reactions; dietary proteins, which are essential nutrients; and increased histamine release, which can cause symptoms of allergies. The ingredient is formulated in solutions that can either be injected or taken sublingually under the tongue. **Potential Toxicity in Cats and Dogs**: Grapes and their derivatives are known to be toxic to both cats and dogs. Even though the exact toxic compound in grapes is not yet identified, ingestion can lead to severe health issues, specifically acute kidney failure. Here are the key points of toxicity: - **Cats**: While less commonly affected than dogs, grapes can still cause toxicity in cats, leading to symptoms such as vomiting, lethargy, abdominal pain, anorexia, and acute kidney failure. Immediate veterinary attention is crucial if ingestion is suspected. - **Dogs**: Dogs are more susceptible to grape toxicity, and even small amounts can lead to severe symptoms including vomiting, diarrhea, abdominal pain, loss of appetite, dehydration, and acute kidney failure. Prompt veterinary care is essential. Intravenous fluids and medications are typically required to manage the symptoms and support kidney function. **Important Note**: Given the potential for severe toxicity, it is crucial to prevent pets from accessing grapes or any grape-containing products, including medications with 'GRAPE' as an active ingredient. Always consult with a veterinarian before administering any new substances to pets.
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